2027 HOTLIST
For introductions to these startups or to request the password to access startup pitch decks, please contact:
Christina Drake
Additional data is available in the master Hotlist database via Airtable:
The Hotlist is a database of promising early-stage companies from Michigan that anticipate raising venture capital in the next 12-18 months.
Startups on the list are those that received the most interest from hundreds of investors at UnDemo Day.
To be included on the Hotlist, startups must have participated in the most recent UnDemo Day event. The list is refreshed each fall, after UnDemo Day.
Current Hotlist companies are shown below, sortable by sector and with embedded links where their pitch decks may be viewed if available.
| Company Name | Primary Sector | Description |
|---|---|---|
| ACASO | Information Technology (IOT, Enterprise, Internet) |
ACASO is an AI operating partner for growing companies. Our agents interview every employee, map how work actually gets done into a company brain, and stay embedded to improve operations week over week. Consulting-grade insight that keeps compounding after the first fix.
|
| Alisio | FinTech |
Alisio is an AI infrastructure layer for manufacturing. We transform factory compliance into a verifiable asset—getting suppliers paid faster, keeping buyers compliant, and helping banks underwrite.
|
| AureSeal, Inc. | Healthcare - Medical Device |
AureSeal is transforming LAA closure with a non-metallic catheter patch that flexes with the heart. Our frame-free design stops peridevice leaks and tissue erosion to improve stroke protection.
|
| Authsnap, Inc. | Healthcare - Services or Health IT |
Authsnap uses clinician-guided AI to turn denied medical claims into winning appeals in minutes—helping hospitals recover earned revenue, reduce costs, and protect patient access to care.
|
| Averra (RoboAuto, Inc DBA Averra Systems) | Advanced Manufacturing / Materials |
Averra is building the operating system for manufacturing, closing the Velocity Gap between engineering and production, starting with structural-scale metal printing, AI, and automation.
|
| Block Harbor | Information Technology (IOT, Enterprise, Internet) |
Block Harbor builds VSEC, the cybersecurity platform for physical AI: connected vehicles, robotics and drones. Live in production at a top-5 global OEM, profitably.
|
| Bloom | Advanced Manufacturing / Materials |
The vetted supply chain service marketplace platform reshaping how hardware is built, delivered, and serviced
|
| Buell Motorcycle Co | Automotive / Mobility |
Relaunch of 40yr old motorcycle OEM formerly owned by Harley Davidson
|
| Capture Tech | Advanced Manufacturing / Materials |
Capture Tech restores waterways with modular biochar systems that remove nutrients and contaminants. Its metagenomic analysis assesses biome health and guides targeted ecosystem recovery.
|
| CatalystXL | Information Technology (IOT, Enterprise, Internet) |
CatalystXL builds the operating foundation enterprises need before AI can succeed.
Most organizations are trying to deploy AI on top of fragmented systems, scattered content, disconnected workflows,
|
| Catapult | Consumer Products |
Catapult helps restaurants generate new revenue by launching and operating virtual brands across delivery marketplaces using their existing kitchens.
|
| ChemCom | Advanced Manufacturing / Materials |
ChemCom's mission is to transform industrial chemistry from a commodity-based product into an intelligent, outcome-driven service that continuously optimizes manufacturing performance.
|
| ConStrat, Inc. | FinTech |
ConStrat is the real-time intelligence layer for construction providing live margin, cash, and risk for contractors and the institutions that fund and insure them.
|
| Coordinista | Healthcare - Services or Health IT |
Coordinista is building the operational infrastructure for decentralized healthcare, helping organizations deploy scarce clinical resources more effectively and improve outcomes.
|
| Coreo, Inc. | Healthcare - Services or Health IT |
Coreo is the AI-powered, EHR-embedded execution layer for cancer care — ensuring every care plan across diagnosis, treatment, and survivorship is actually carried out, not just documented.
|
| Crank Bio | Healthcare - Biotech/Pharma |
Crank Bio is pioneering a new class of RNA antisense-based therapies called small nuclear guide RNAs (SNuG-RNAs). SNuG-RNAs are a one-time for human genetic diseases, including blindness and deafness.
|
| Cura Collaborative, Inc. | Healthcare - Services or Health IT |
Cura Collaborative closes the gap in healthcare's Grey Area. Led by founders behind one of Henry Ford Health's most successful exits (CarepathRx), we partnered with HFH again to drive ROI. Raising $5M
|
| CVR (Common Vector Robotics) | Automotive / Mobility |
Common Vector Robotics builds American-made, NDAA-compliant ground robots in Detroit. Vertical integration lets us field at $50K what everyone else fields at $500K.
|
| DealBlazer | FinTech |
DealBlazer is an AI transaction coordination platform that runs a real estate deal from contract to close reading the purchase agreement, tracking every deadline, and compliance warnings for broker's.
|
| Decimal Code | Healthcare - Services or Health IT |
Decimal Code is an automated medical coding & CDI spinout from Michigan Medicine, focused on the perioperative space.
|
| Diapin Therapeutics, Inc. | Healthcare - Biotech/Pharma |
Diapin Therapeutics is developing life saving treatments for cardiovascular and metabolic diseases.
|
| Electric Outdoors Inc | Energy / Energy Efficiency |
Electric Outdoors builds AI-powered portable microgrids that combine energy, water, and connectivity into rapidly deployable infrastructure for outdoor hospitality, utilities, and defense and more
|
| ElectricFish Energy Inc. | Energy / Energy Efficiency |
ElectricFish develops, and operates distributed 400 kWh battery nodes that use premium EV charging to fund deployment and grid services to increase lifetime returns.
|
| Extrinsic Immunity Therapeutics | Healthcare - Biotech/Pharma |
Extrinsic Immunity Therapeutics, LLC is pioneering a new era of targeted oncology therapeutics and diagnostic tools by leveraging NET technology.
|
| Flightpath Biosciences, Inc | Healthcare - Biotech/Pharma |
Clinical-stage life sciences company targeting causal pathogens that initiate or exacerbate complex diseases in Cancer, IBD and Infectious Diseases. Company has lead investor and signed Series B TS.
|
| Gavelon AI | Information Technology (IOT, Enterprise, Internet) |
AI legal workspace powered by proprietary legal intelligence, helping lawyers research, draft, and analyze across fragmented legal jurisdictions.
|
| General Orbit | Automotive / Mobility |
General Orbit turns the Earth's magnetic field into positioning that cannot be jammed, on any vehicle from the seabed to orbit. We are building the first universal, unjammable positioning layer.
|
| Genomenon | Healthcare - Services or Health IT |
Genomenon is a genomic intelligence & real-world evidence AI company delivering the underlying knowledge layer for genetic interpretation and patient level RWE for pharma applications.
|
| Geo Prime Energy | Energy / Energy Efficiency |
GeoPrime Energy develops modular, hybrid energy infrastructure for data centers, municipalities, industrial sites, hospitals, and innovation districts that require reliable, scalable, and resilient po
|
| Great Lakes Crystal Technologies, Inc. | Advanced Manufacturing / Materials |
GLCT produces the highest quality single crystal diamond substrates and epiwafers for deep tech hardware applications.
|
| Health Exam | Healthcare - Services or Health IT |
Health Exam deploys AI agents that automate healthcare operations, connecting patients, providers, and workflows to move care forward between visits while reducing administrative burden.
|
| HealthyLifetime, Inc. | Healthcare - Services or Health IT |
HealthyLifetime helps healthcare teams improve outcomes and independence by tracking behavior change. IHBC
shows early signs that coaching is working and tied to ROI.
|
| Hush | Consumer Products |
Hush reveals everything the internet knows about you, then removes it. AI detection and remediation with expert-led support. Protection for you, your family, and your workforce.
|
| Innostrat Technologies Inc | Advanced Manufacturing / Materials |
Innostrat™ Technologies Inc. Is an engineering and R&D, advanced manufacturing company with expertise in automation, robotics, machine vision, AI driven quality systems.
|
| Intelycx | Information Technology (IOT, Enterprise, Internet) |
Intelycx is building the AI operating layer for modern manufacturing — helping factories connect equipment, automate quality, empower frontline teams, and move toward autonomous operations.
|
| JustAir | Information Technology (IOT, Enterprise, Internet) |
JustAir is the verification layer for air quality data. We measure air block by block, grade whether every reading can be trusted, and serve it to the cities, agencies for action.
|
| Keryx Inc | Healthcare - Biotech/Pharma |
At Keryx, our nucleic-acid-based therapeutic restores insulin cell function to reverse or prevent type-2 diabetes, transforming it from a chronic disease into a preventable condition.
|
| Kittali Weidner LLC | Information Technology (IOT, Enterprise, Internet) |
Raw materials costs keep shifting and EPR regulations are expanding from 7 to 33 states. RHEO gives manufacturers the decision intelligence to proactively forecast, optimize, and act on their costs.
|
| KMI Space | Automotive / Mobility |
In-space logistics company with "tow trucks in space" for critical space assets. Following 2024-25 ISS demonstrations, KMI Space is delivering defense-first capabilities for surging dual-use demand.
|
| Layer1Labs Silicon Inc | Energy / Energy Efficiency |
Layer1Labs Silicon develops deterministic orchestration architecture for heterogeneous compute, recovering lost compute capacity in hyperscale AI infrastructure.
|
| Livsee | FinTech |
Livsee provides agentic AI chat services to multifamily and then operationalizes the data to infrom pricing and other decisions that impact NOI.
|
| Machine AI Solutions LLC | Information Technology (IOT, Enterprise, Internet) |
Machine AI Solutions is an end-to-end AI factory operating system that turns trapped machine data into real-time decisions, helping small & mid-sized manufacturers cut downtime and boost throughput.
|
| Manhattan Neuroscience | Healthcare - Biotech/Pharma |
Manhattan Neuroscience develops disease-modifying medicines for neurodegenerative disease by using AI to decode and engineer the regulatory biology underlying human cognition.
|
| Marel Power Solutions | Energy / Energy Efficiency |
MAREL builds ultra-compact, modular power hardware that makes electricity conversion smaller, lighter, scalable, and cheaper to deploy across mobility, grid, data centers, defense, & renewables.
|
| Mbility Inc | Automotive / Mobility |
Mbility is an early-stage startup developing an integrative AI, RFID, and IoT-enabled logistics platform that mitigates risks and improves business continuity, safety and wellbeing in asset management
|
| Medication Data Science (MeDS) | Healthcare - Services or Health IT |
MeDS is an AI-powered platform building the autonomous pharmacy by eliminating medication errors, automating workflows, and improving productivity.
|
| MELD Health, Inc | Healthcare - Services or Health IT |
Clinical solution for chronic pain management through AI-augmented, asynchronously reported patient symptom data, summarized and structured with clinical insights, expediting EHR data integration
|
| Mentavi Health | Information Technology (IOT, Enterprise, Internet) |
Mentavi Health addresses the significant and rapidly growing total addressable marketing of mental health needs. Mentavi provides a telehealth based diagnostic and treatment approach and platform.
|
| Michigan Space Technologies | Advanced Manufacturing / Materials |
Michigan Space Technologies is developing Caelus, an electromagnetic-assisted launch platform designed to redefine responsive access to space. MiST is building the infrastructure layer for lower-cost
|
| Modal Motors, Inc. | Automotive / Mobility |
We are an American electric motor manufacturer that manufactures our Non-Rare-Earth motors here in the Detroit area that outperform foreign and competitor Rare-Earth motors at a fraction of their cost
|
| moneyba11 | FinTech |
moneyba11 converts sports bettors into traders. We are the analytics that translates any bet into the same position in a prediction market or brokerage, becoming the conversion funnel for these venues
|
| Motmot | Information Technology (IOT, Enterprise, Internet) |
Motmot lets utilities, engineers, & contractors investigate water main. We sign platform agreements with customers and earn revenue each time the equipment is deployed.
|
| Noble Gas Systems Inc. | Advanced Manufacturing / Materials |
Noble Gas is a developer and producer of conformable high-pressure gas storage systems for industrial gas, energy, and mobility applications.
|
| Oprones | Automotive / Mobility |
Oprones develops autonomous drone systems and a drone-agnostic control and analytics platform for infrastructure inspection, disaster response, and industrial monitoring.
|
| Ottawa Infotainment | Automotive / Mobility |
Ottawa Infotainment builds software and electronics for next-gen vehicles. Our anchor customer has paid $2.7M to date, and customers span automotive, off-highway, commercial, and defense.
|
| PainTools | Healthcare - Services or Health IT |
PainTools is a personalized digital health platform using proprietary AI and human engagement to help women with chronic pain achieve lasting symptom improvement.
|
| Praxigen | Healthcare - Services or Health IT |
Praxigen helps specialty practices handle prior authorization end to end: payer lookup, documentation and code checks, case tracking, and cited appeals, all in one workspace.
|
| ProbeTruth | Information Technology (IOT, Enterprise, Internet) |
Deepfake detection for videos, audios and images (using AI reasoning and learning)
|
| PYPE | Healthcare - Services or Health IT |
PYPE is an AI-powered compliance automation platform that helps human services organizations reduce caseworker burden by automatically handling documentation, reporting, and regulatory requirements.
|
| RIVET Work Inc | Information Technology (IOT, Enterprise, Internet) |
RIVET is a labor planning and workforce management software for mid-market and large construction specialty contractors.
|
| Robobuoy Inc. | Media / Entertainment / Sports |
Robobuoy is a robotics company disrupting the marine industry. Our Bots have served as racecourse marks, golf targets, event boundaries and military drones.
|
| RoborQ Inc. | Advanced Manufacturing / Materials |
RoborQ builds cloud compliance software (Core) and offline Edge-AI servers (Preempt). We ingest raw telemetry to automate shop-floor CAPA and parts WO/POs completely offline.
|
| Scalable AI | Information Technology (IOT, Enterprise, Internet) |
Scalable AI is a Platform of Vertical AI Agents that automate the most mission critical processes for mid market manufacturers, built to integrate seamlessly into legacy ERPs
|
| SecuritySnares, Inc. | Information Technology (IOT, Enterprise, Internet) |
SecuritySnares helps organizations reduce the likelihood that ransomware progresses to business-disrupting encryption while preserving protective controls against common tampering techniques.
|
| Swept | Information Technology (IOT, Enterprise, Internet) |
Swept AI is trust infrastructure for enterprises deploying AI in regulated industries, providing supervision, benchmarking, and monitoring to keep AI agents compliant and safe. Think HR for AI workers
|
| Synergy HIM Tech | Healthcare - Services or Health IT |
Himio (Synergy HIM Tech) is an AI platform that suggests, validates, and audits hospital ICD-10 coding inside Epic recovering ~$565K per hospital per year in documented but unbilled care.
|
| TerraKinesis | Information Technology (IOT, Enterprise, Internet) |
PULSE by TerraKinesis is mesh-networking software for existing tactical radios, enabling reliable communication across 1,000+ nodes without satellite or server dependency for defense and automotive.
|
| Tour | Marketing / Advertising / Sales |
Tour enables property managers to digitize & embed their best salesperson’s guided tour on their website, in automate competitor research with AI. Backed by Y Combinator & Jason Calacanis. $2.1M Rev
|
| VERN AI | Information Technology (IOT, Enterprise, Internet) |
VERN AI builds VERN OS, control infrastructure that turns preferred LLMs into governable, outcome-driven AI across chat, voice, avatars, agents, robots, and human-facing systems.
|
| Volt Harbor, Inc. | Energy / Energy Efficiency |
We deliver the entire front-end Power Stack from the grid to the Data Center building in a universal software-defined hardware platform all in one box.
|
| Wave Lumina Inc. | Advanced Manufacturing / Materials |
Wave Lumina is building a field-ready sensor that measures PFAS “forever chemicals” at the sample point — turning weeks of lab turnaround into actionable decisions that can be made in minutes on site.
|
| Xmore AI, Inc. | Information Technology (IOT, Enterprise, Internet) |
Xmore AI develops Agentic AI cybersecurity solutions that automate threat detection, investigation, and response.
|
| Zoris.AI | Advanced Manufacturing / Materials |
Zoris turns simple text into production-ready CAD drawings. It enables faster designs creation, improves material efficiency.
|
Close
Enter Password
The content you are attempting to access is password protected. To continue, enter the password below.